What semaglutide actually costs
By Open Water Rx Editorial Team, Publisher and buyer-guide research
Reviewed Rechecked monthly
Short answer
How much does semaglutide cost on a recorded program?
Recorded semaglutide prices sit below the tirzepatide lines at comparable programs. The active comparison is compounded and self-pay: a bundled price covers the medication plan, recorded here from $169 a month with no separate membership fee, and the charge repeats each period.
A monthly membership with a branded drug such as Wegovy billed separately is common in the wider market. Programs built that way are not directly comparable to a self-pay medication package, so they sit outside this guide’s comparison scope and are not carried in the active ledger.
Recorded options
The active comparison carries compounded, consumer-direct semaglutide programs, each priced a period at a time. A bundled price is not the same as no recurring billing: the charge still repeats.
On the criterion of no separate membership fee, two recorded programs qualify, Surfbound Health semaglutide and Henry Meds compounded semaglutide, so both are listed rather than a single pick. Every criterion, with all the programs that meet each one, sits in the criteria matrix.
Choose by what you need
- A bundled price
- Look for one figure that covers the medication plan, then confirm its billing cadence rather than assuming it is monthly.
- A branded product
- Expect a membership plus a separately billed drug, and a drug line that differs between the oral pill and the injectable pen.
- A predictable payment
- Check whether the price steps up by dose. A bundled compounded rate can stay flat, while a branded drug line often rises.
Sourcing
Every semaglutide figure is tied to a provider page and dated. Where a program prices by dose or product, the figure is the advertised starting point for the medication line only, never a combined total with a membership.
The compounded option recorded here is not FDA-approved and makes no equivalence claim to a branded drug such as Wegovy or Ozempic; the FDA sets out the risks of compounded drugs (opens in a new tab).
Suggested citation
GLP1 Buyer Guide. "What semaglutide actually costs." Open Water Rx LLC, last modified October 15, 2026. https://glp1buyerguide.com/semaglutide/cost
Recorded monthly charges at a glance
Each bar is a program’s lowest recorded recurring charge for one month, in scope for this page. The lowest is picked out in brass; a program with no verified charge is left out rather than shown as zero.
- NovoCare PharmacySemaglutide$149/mo
- Surfbound HealthSemaglutide$169/mo
- Fifty 410Semaglutide$199/mo
- Henry MedsSemaglutide$297/mo
- DirectMedsSemaglutide$297/mo
- RoSemaglutide$298/mo
- TrimRxSemaglutide$299/mo
- Remedy MedsSemaglutide$299/mo
Bars show the lowest recorded recurring monthly charge per program; they are not a ranking and not a recommendation. A blank in the ledger means the charge is unverified, so that program does not appear here.
Recorded offers and their prices
We show only the standard recurring monthly price. Introductory and first-month discounts, package deals, prepaid bundles and multi-month or annual plans are never shown, because none of them is the price a member keeps paying.
Values we could not verify stay blank. The full set of offers lives in the comparison ledger.
Disclosure: GLP-1 Buyer Guide is operated by Open Water Rx LLC, which also operates Surfbound Health. Our methodology
| Provider | Regular one-month price | Membership fee / month | Medication price | Cost of 12 monthly charges | Billing interval | Commitment | Required fees | Sources | |
|---|---|---|---|---|---|---|---|---|---|
| DirectMedsSemaglutide · Compounded · not FDA-approved | $297 per month | $0No separate membership fee | $297 per month | $297 per monthStandard monthly rate. | $3,564 | MonthlyBilled monthly; a four-week cycle is treated as one month. | Monthly; no stated minimum term. | No separate membership fee; evaluation, supplies and shipping included. | |
| Fifty 410Semaglutide · Compounded · not FDA-approved | $199 per month, pay as you go | $0No separate membership fee | $199 per month | $199 per monthPay as you go, no recurring contract; one month of medication per monthly shipment. | $2,388 | MonthlyBilled monthly; a four-week cycle is treated as one month. | Pay as you go, no automatic renewal. | No separate membership fee; consultation and follow-up included. | |
Henry MedsSemaglutide · Compounded · not FDA-approved
| $297/month injectable; oral from $249/month | $0Bundled into the program price; no separate membership billing | From $297/mo (injectable); oral from $249/mo | From $249/moBundled price; the oral form starts at $249/mo and the injectable at $297/mo. This is the lowest advertised floor. | $3,564 | MonthlyBilled monthly. | Monthly billing; cancelling stops future charges. | Bundled. A separate membership amount is not established. | |
NovoCare PharmacySemaglutide · FDA-approved brand · Wegovy
| Pen $349 per month; pill $149 to $299 per month, by dose | $0$0, no separate membership fee | Wegovy pen $349 per month (all standard doses), $399 per month (Wegovy HD 7.2 mg); Wegovy pill $149 (1.5 mg), $199 (4 mg), $299 (9 mg and 25 mg) | From $149 per month (pill, 1.5 mg); pen $349 per monthThe pill is the lower line. The pen is a single price across the standard doses, separate from the pill ladder. | From $1,788 | MonthlyBilled monthly; a four-week cycle is treated as one month. | Not established. No subscription or membership is attached to the pharmacy price; fills repeat while the prescription stays active. | No membership fee. NovoCare Pharmacy is a self-pay pharmacy and requires a valid prescription. Insurance is not accepted. | |
| Remedy MedsSemaglutide · Compounded · not FDA-approved | $299 per month, flat across doses | $0No separate membership fee | $299 per month | $299 per monthStandard flat monthly rate. | $3,588 | MonthlyBilled monthly; a four-week cycle is treated as one month. | No commitment; cancel any time. | No separate fees. Price-lock guarantee. | |
| RoSemaglutide · FDA-approved brand · Wegovy | $149 membership plus medication | $149/mo$149 | From $149 per month (Wegovy pill, 1.5 mg), billed separately | From $298 per month ($149 membership plus medication from $149)Membership and medication are two separate monthly lines; the combined figure is a floor at the lowest advertised drug price. | From $3,576 | MonthlyBilled monthly; a four-week cycle is treated as one month. | Month-to-month membership. | Membership fee required in addition to medication. | |
| Surfbound HealthSemaglutide · Compounded · not FDA-approved | $169 per month | $0No separate membership fee | $169 | $169 per monthFlat price with no advertised dose-based increase. Billed monthly; one month of medication per charge. | $2,028 | MonthlyBilled monthly; a four-week cycle is treated as one month. | No long-term commitment. Recurring billing applies until you cancel. | No separate membership fee. Consultation $0. Shipping included. Required lab charges, if any, are not publicly verified. | |
| TrimRxSemaglutide · Compounded · not FDA-approved | $299 per month | $0No separate membership fee | $299 per month | $299 per monthStandard month-to-month rate. | $3,588 | MonthlyBilled monthly; a four-week cycle is treated as one month. | A month-to-month option is available with no minimum term. | No separate membership fee; consultation, supplies and shipping included. |
Recorded semaglutide offers across providers. Values we could not verify stay blank. Read from official public webpages, not checkout transactions.
DirectMeds
Semaglutide · Compounded · not FDA-approved
- Regular one-month price
- $297 per month
- Membership fee / month
- $0No separate membership fee
- Medication price
- $297 per month
- Total monthly
- $297 per monthStandard monthly rate.
- Cost of 12 monthly charges
- $3,564
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- Monthly; no stated minimum term.
- Required fees
- No separate membership fee; evaluation, supplies and shipping included.
- Evidence
- directmeds.com/portal/products/semaglutide-injection (opens in a new tab)Checked October 15, 2026 · Source-checked
Fifty 410
Semaglutide · Compounded · not FDA-approved
- Regular one-month price
- $199 per month, pay as you go
- Membership fee / month
- $0No separate membership fee
- Medication price
- $199 per month
- Total monthly
- $199 per monthPay as you go, no recurring contract; one month of medication per monthly shipment.
- Cost of 12 monthly charges
- $2,388
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- Pay as you go, no automatic renewal.
- Required fees
- No separate membership fee; consultation and follow-up included.
- Evidence
- www.fifty410.com/pricing/semaglutide (opens in a new tab)Checked October 15, 2026 · Source-checkedListed as a pay-as-you-go monthly option with no recurring contract.
- www.fifty410.com/refund-policy (opens in a new tab)Checked October 15, 2026 · Source-checkedFull refund before the pharmacy begins compounding; no routine refund after compounding begins or after shipping; damaged or lost orders reviewed within 48 hours.
Henry Meds
Semaglutide · Compounded · not FDA-approved
- Compounded injectable semaglutide ($297/month, flat across doses)
- Compounded oral semaglutide (From $249/month)
- Regular one-month price
- $297/month injectable; oral from $249/month
- Membership fee / month
- $0Bundled into the program price; no separate membership billing
- Medication price
- From $297/mo (injectable); oral from $249/mo
- Total monthly
- From $249/moBundled price; the oral form starts at $249/mo and the injectable at $297/mo. This is the lowest advertised floor.
- Cost of 12 monthly charges
- $3,564
- Billing interval
- MonthlyBilled monthly.
- Commitment
- Monthly billing; cancelling stops future charges.
- Required fees
- Bundled. A separate membership amount is not established.
- Evidence
- henrymeds.com/legal/programs (opens in a new tab)Checked October 15, 2026 · Source-checkedRecorded from the dated program schedule; oral semaglutide is lower.
- henrymeds.com/legal/programs (opens in a new tab)Checked October 15, 2026 · Conflicting sourcesThe schedule mixes products and durations, so a single flat figure is not treated as verified.
- henrymeds.com/faq (opens in a new tab)Checked October 15, 2026 · Source-checked
- henrymeds.com/legal/terms-of-service/ (opens in a new tab)Checked October 15, 2026 · Source-checked
- henrymeds.com/legal/rrr-policy (opens in a new tab)Checked October 15, 2026 · Source-checkedThe $30 consult component sits inside the bundled billing, not as an extra surcharge.
NovoCare Pharmacy
Semaglutide · FDA-approved brand · Wegovy
- Wegovy pen ($349/month for all standard doses; $399/month for Wegovy HD 7.2 mg)
- Wegovy pill ($149/month (1.5 mg), $199/month (4 mg), $299/month (9 mg and 25 mg))
- Regular one-month price
- Pen $349 per month; pill $149 to $299 per month, by dose
- Membership fee / month
- $0$0, no separate membership fee
- Medication price
- Wegovy pen $349 per month (all standard doses), $399 per month (Wegovy HD 7.2 mg); Wegovy pill $149 (1.5 mg), $199 (4 mg), $299 (9 mg and 25 mg)
- Total monthly
- From $149 per month (pill, 1.5 mg); pen $349 per monthThe pill is the lower line. The pen is a single price across the standard doses, separate from the pill ladder.
- Cost of 12 monthly charges
- From $1,788
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- Not established. No subscription or membership is attached to the pharmacy price; fills repeat while the prescription stays active.
- Required fees
- No membership fee. NovoCare Pharmacy is a self-pay pharmacy and requires a valid prescription. Insurance is not accepted.
- Evidence
- www.novocare.com/obesity/products/wegovy.html (opens in a new tab)Checked October 18, 2026 · Source-checkedPen $349 across the standard doses and $399 for Wegovy HD 7.2 mg; pill $149 (1.5 mg), $199 (4 mg), $299 (9 mg and 25 mg). No membership fee; insurance is not accepted.
Remedy Meds
Semaglutide · Compounded · not FDA-approved
- Regular one-month price
- $299 per month, flat across doses
- Membership fee / month
- $0No separate membership fee
- Medication price
- $299 per month
- Total monthly
- $299 per monthStandard flat monthly rate.
- Cost of 12 monthly charges
- $3,588
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- No commitment; cancel any time.
- Required fees
- No separate fees. Price-lock guarantee.
- Evidence
- remedymeds.com/medication/comp-sema-inj (opens in a new tab)Checked October 15, 2026 · Source-checkedFlat across doses.
Ro
Semaglutide · FDA-approved brand · Wegovy
- Regular one-month price
- $149 membership plus medication
- Membership fee / month
- $149/mo$149
- Medication price
- From $149 per month (Wegovy pill, 1.5 mg), billed separately
- Total monthly
- From $298 per month ($149 membership plus medication from $149)Membership and medication are two separate monthly lines; the combined figure is a floor at the lowest advertised drug price.
- Cost of 12 monthly charges
- From $3,576
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- Month-to-month membership.
- Required fees
- Membership fee required in addition to medication.
- Evidence
- ro.co/weight-loss/pricing/ (opens in a new tab)Checked October 18, 2026 · Source-checkedThe membership and the medication are billed as separate monthly lines.
Surfbound Health
Semaglutide · Compounded · not FDA-approved
- Regular one-month price
- $169 per month
- Membership fee / month
- $0No separate membership fee
- Medication price
- $169
- Total monthly
- $169 per monthFlat price with no advertised dose-based increase. Billed monthly; one month of medication per charge.
- Cost of 12 monthly charges
- $2,028
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- No long-term commitment. Recurring billing applies until you cancel.
- Required fees
- No separate membership fee. Consultation $0. Shipping included. Required lab charges, if any, are not publicly verified.
- Evidence
- surfbound.co/semaglutide (opens in a new tab)Checked October 15, 2026 · Source-checkedCharged after the medication request is approved.
- surfbound.co/semaglutide (opens in a new tab)Checked October 15, 2026 · Source-checked
- surfbound.co/semaglutide (opens in a new tab)Checked October 15, 2026 · Owner-confirmedConfirmed by Open Water Rx LLC on October 15, 2026; billed monthly.
- surfbound.co/pricing (opens in a new tab)Checked October 15, 2026 · Source-checked
- surfbound.co/pricing (opens in a new tab)Checked October 15, 2026 · Source-checked
- surfbound.co/refund (opens in a new tab)Checked October 15, 2026 · Source-checked
- surfbound.co/refund (opens in a new tab)Checked October 15, 2026 · Source-checkedSource: the published Refund Policy, which takes precedence over the Terms for refund matters.
- surfbound.co/locations (opens in a new tab)Checked October 15, 2026 · Source-checkedA state directory is not a fulfillment guarantee.
- surfbound.co/pricing (opens in a new tab)Checked October 15, 2026 · Owner-confirmedConfirmed by Open Water Rx LLC on October 15, 2026; each monthly charge buys a one-month supply. The exact medication days per charge (28 or 30) are kept internally as unverified and are not displayed.
- surfbound.co/pricing (opens in a new tab)Checked October 15, 2026 · Source-checkedFlat across the available prescribed doses; the minimum and maximum doses offered are not publicly verified.
- surfbound.co/refund (opens in a new tab)Checked October 15, 2026 · Conflicting sourcesThe published Refund Policy uses “has processed”, while the Terms use “enters pharmacy processing”. The Refund Policy takes precedence for refunds; the difference is flagged, not resolved by changing the provider’s policy.
TrimRx
Semaglutide · Compounded · not FDA-approved
- Regular one-month price
- $299 per month
- Membership fee / month
- $0No separate membership fee
- Medication price
- $299 per month
- Total monthly
- $299 per monthStandard month-to-month rate.
- Cost of 12 monthly charges
- $3,588
- Billing interval
- MonthlyBilled monthly; a four-week cycle is treated as one month.
- Commitment
- A month-to-month option is available with no minimum term.
- Required fees
- No separate membership fee; consultation, supplies and shipping included.
- Evidence
- trimrx.com/terms-and-conditions (opens in a new tab)Checked October 18, 2026 · Source-checkedTerms list $299 per month on the month-to-month plan.
Cost of 12 monthly charges is the standard monthly price multiplied by 12. It is a derived figure, not a quoted price. It is labelled “from” for a program priced by dose, and stays blank where no standard monthly price is verified. See how we compare.
Questions about semaglutide cost
What drives the difference, and whether a membership ever lowers the total.
Two things: whether a separate membership is added, and whether the drug is branded or compounded. A bundled compounded plan tends to show one number, while a membership-plus-branded plan shows a membership and a separate medication line.
Last modified . Facts carry the date we checked the provider page behind them.